CAS 59-46-1 Procaine China factory supply lower price high purity high quality

CAS 59-46-1 Procaine China factory supply lower price high purity high quality
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Common Name Procaine
CAS Number 59-46-1 Molecular Weight 236.310
Density 1.1±0.1 g/cm3 Boiling Point 373.6±22.0 °C at 760 mmHg
Molecular Formula C13H20N2O2 Melting Point 61ºC
Density 1.1±0.1 g/cm3
Boiling Point 373.6±22.0 °C at 760 mmHg
Melting Point 61ºC
Molecular Formula C13H20N2O2
Molecular Weight 236.310
Flash Point 179.8±22.3 °C
Exact Mass 236.152481
PSA 55.56000
LogP 2.36
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.543
Description Procaine is a local anesthetic with a para-amino function. Sensitization mainly concerns medical, dental and veterinary professions.
Chemical Properties The hydrochloride salt of 2-(diethylamino) ethyl p-aminobenzoate (C13H21ClN2O2 or N2C6H4COOCH2CH2NH(C2H5)2HCl) is generally referred to as procaine. Although the PABA ester is insoluble in water, the hydrochloride salt is very soluble in water.
Uses Procaine (Novocain) is mainly used in dental or medical procedures requiring infiltration anesthesia, peripheral block, or spinal block.
Uses Procaine is a sodium channel blocker and inhibitor of a variety of processes.
Definition ChEBI:Procaine is a benzoate ester, formally the result of esterification of 4-aminobenzoic acid with 2-diethylaminoethanol but formed experimentally by reaction of ethyl 4-aminobenzoate with 2-diethylaminoethanol. It has a role as a local anaesthetic, a central nervous system depressant, a peripheral nervous system drug and a drug allergen. It is a benzoate ester, a substituted aniline and a tertiary amino compound. It is functionally related to a 2-diethylaminoethanol and a 4-aminobenzoic acid. It is a conjugate base of a procaine(1+).
Procaine was synthesized in 1904 to address the chemical instabilityof cocaine and the local irritation it produced. The pKa of procaine is 8.9; it has low lipid solubility and the estergroup is unstable in basic solutions. Procaine is available inconcentrations ranging from 0.25% to 10% with pHs adjustedto 5.5 to 6.0 for chemical stability. Procaine is also includedin some formulations of penicillin G to decrease the pain ofintramuscular injection.